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苏丹东部的乳腺癌负担:为期七年的回顾性研究
Ahmed Balla M Ahmed1, Salma Alrawa1, Ahmed A Yeddi1
1Faculty of Medicine, University of Khartoum, Khartoum 11111, Sudan.
Ecancermedicalscience
|July 18, 2024
概括
苏丹东部的乳腺癌通常影响年轻女性,并且在晚期呈现. 癌症家族病史可能会对晚期诊断提供保护.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 乳腺癌 (BC) 是苏丹的一个重大健康问题,东部地区的流行病学数据有限.
- 这项研究解决了东苏丹BC人口统计和临床病理特征信息的缺乏.
- 专注于在加达里夫州东部瘤中心 (EOC) 接受治疗的患者.
研究的目的:
- 描述苏丹东部乳腺癌患者的人口统计和临床病理学特征.
- 为了确定与晚期乳腺癌诊断相关的因素.
- 提供对以前研究不足的地区乳腺癌流行病学的见解.
主要方法:
- 在EOC (2016-2022) 治疗的394名乳腺癌患者的横截面研究.
- 使用描述性统计和多重物流回归分析医疗记录.
- 统计学意义是通过p值<0.05来确定的.
主要成果:
- 诊断时的中位数年龄为48岁,96%的患者是女性.
- 晚期 (III和IV) 占诊断的82%.
- 三重阴性乳腺癌 (TNBC) 的患病率为43%;较高的BC等级和较低的教育程度与高级阶段有关.
- 癌症家族病史与晚期疾病风险降低有关 (OR:0.38).
结论:
- 东苏丹的乳腺癌经常在年轻时和晚期出现,显著的比例是三阴性BC.
- 家庭癌症史似乎是防止晚期癌症呈现的保护因素.
- 更高的癌症等级是晚期乳腺癌的重要危险因素.
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