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Updated: Jun 20, 2025

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BTLA和PD-1信号减弱了TCR介导的转录组变化.

Muhammad Zainul Arifin1, Judith Leitner2, Donagh Egan1

  • 1Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.

iScience
|July 18, 2024
PubMed
概括

像PD-1和BTLA这样的免疫检查点会抑制T细胞受体信号传递. 比PD-1更强烈地抑制BTLA的基因表达变化,突出了它们在癌症治疗中的作用.

关键词:
分子生物学分子生物学文字转录学 (Transcriptomics) 是一个学科.

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