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表面修改型眼内透镜对长期术后抑制后囊变暗的作用

Mayumi Nagata¹, Hiroyuki Matsushima¹, Tadashi Senoo¹

¹Department of Ophthalmology, Dokkyo Medical University, 880 Kitakobayashi, Mibu City, Tochigi, 321-0293, Japan.

|July 18, 2024

概括

一种新的表面修饰眼内透镜 (XY1) 与标准透镜 (FY-60AD) 相比,在10年内显著降低了后囊不透明. 这种表面修改增强了附着性,有效地防止白内障手术后后背囊变暗.

科学领域:

眼科医生眼科眼科
生物材料科学生物材料科学
医学光学医学光学

背景情况:

后囊模糊化 (PCO) 是白内障手术后的一个常见并发症.
现有的眼内透镜 (IOL) 在设计和材料上有所不同,影响PCO率.
预防PCO对于长期的视觉结果至关重要.

研究的目的:

为了比较5年后PCO的发生率和10年后Neodymium-yttrium-aluminum-garnet (Nd:YAG) 囊切除率.
为了评估表面修饰IOL (XY1) 与标准IOL (FY-60AD) 在预防PCO的有效性.
评估增强后囊粘附在PCO预防中的作用.

主要方法:

一个随机的,受控的,前性的,单盲研究,与个体内比较.
30名患者 (60只眼睛) 接受了双边白内障手术,使用一个XY1和一个FY-60AD IOL.
使用Scheimpflug成像 (EAS-1000) 来通过分散光强度量化PCO.

主要成果:

在手术后5年,XY1组的散射光值明显较低 (6.50 ± 5.69),相比于FY-60AD组 (11.64 ± 5.30).
在术后10年,XY1组的Nd:YAG囊切除的累积发病率为74.8%,FY-60AD组为13.8%.
表面修改的XY1 IOL在十年内显示了PCO发病率的持续减少.

结论:

修改眼内透镜的表面以增强囊粘附是防止后囊变暗的有效策略.
与FY-60AD IOL相比,XY1 IOL及其表面处理提供了优越的长期PCO预防.
这项研究强调了先进的IOL表面技术在改善白内障手术后患者结果方面的临床益处.

关键词:

眼内透镜的眼内镜片是什么?新石榴石的囊形术.后部囊变暗,使其变暗.散射光的强度是分散光的强度.表面的修改是表面的修改.

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