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食物过敏和亚托皮性皮肤炎
Tina Banzon1, Donald Y M Leung2, Lynda C Schneider1
1From the Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, MA, and.
亚托皮肤炎 (AD) 与食物过敏 (FA) 的更高风险有关. 在AD患者中对FA的测试应基于临床病史,而不仅仅是敏感化,以避免不必要的饮食.
科学领域:
- 皮肤病学 皮肤病学
- 过敏学 过敏学
- 免疫学 免疫学 免疫学
背景情况:
- 亚托匹性皮肤炎 (AD) 是一种慢性炎症性皮肤疾病,引起强烈的和病变.
- 阿尔茨海默病与患食物过敏 (FA) 的风险增加有关,特别是在儿童中.
- 阿尔茨海默氏症的皮肤炎症可能会损害皮肤屏障,增加对过敏原和刺激物的敏感性.
研究的目的:
- 审查亚托皮性皮肤炎和食物过敏之间的关系.
- 讨论食物过敏测试对阿兹海默症患者的影响.
- 在AD的背景下,为适当的食物过敏评估提供指导.
主要方法:
- 关于研究阿尔茨海默氏症和阿尔茨海默氏症之间的联系的文学评论.
- 对阿尔茨海默病患者群体中FA患病率的数据分析.
- 在AD患者中对FA的诊断方法的评估.
主要成果:
- 患有中度至重度AD的儿童患有免疫球蛋白E (IgE) 介导的FA的患病率显著更高.
- 食物挑战可以重现AD症状,避免饮食可以改善AD.
- 在AD中食物敏感性并不总是等同于临床过敏,消除饮食带有风险.
结论:
- 虽然阿尔茨海默氏症和阿尔茨海默氏症有关,但消除饮食不是一种治疗方法,可以导致营养缺乏和过敏反应等不良结果.
- 在AD患者的食物过敏测试应以立即过敏反应的临床病史为指导.
- 建议对患有AD的婴儿进行测试,这些婴儿对最佳的皮肤护理没有反应,或者在摄入食物时有明显的过敏症状.
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