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丸超声波微血管密度在评估精子生成和预测成功的精子检索时

Jun Cui¹, Wei Fu², Yongsheng Song¹

¹Second Department of Urology, Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China.

Quantitative imaging in medicine and surgery

|July 18, 2024

概括

超声波微血管密度 (UMVD) 和超声波体积估计 (UVE) 可以预测非阻塞性精子缺血症 (NOA) 的男性的精子检索成功. 结合这些超声波测量方法,为指导微切割丸精子提取 (micro-TESE) 程序提供了一种有价值的工具.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
生殖医学生殖医学
医疗成像医学成像

背景情况:

微循环障碍和丸精子生成具有显著的临床意义.
了解丸微循环和精子生产之间的联系对于生育治疗至关重要.

研究的目的:

调查丸微循环和精子生成之间的相关性.
评估超声波微血管密度 (UMVD) 和超声波体积估计 (UVE) 的预测值,以成功检索非阻塞性精子缺血症 (NOA) 的男性的精子.

主要方法:

一项前性观察性研究,涉及875名参与者.
用Angio PLUSTM Planwave超敏感成像 (AP) 来测量丸的UMVD和UVE.
参与者被分为不同的精液分析组,包括NOA.

主要成果:

不同的精液组之间没有观察到平均UMVD的显著差异.
在接受微切割丸精子提取 (micro-TESE) 的NOA患者中,成功提取精子的病例与未成功病例相比,在UMVD和UVE中显示出显著差异 (P<0.01).
结合UMVD和UVE显示了高诊断性能 (AUC:0.856) 预测微型TESE的成功,确定了最佳切断值.

结论:

在微型TESE之前,AP衍生的UMVD和UVE是成功提取精子的有价值的预测工具.
UMVD和UVE的组合提供了一个强大的诊断方法来预测微型TESE的结果.
针对UMVD (>28.50/cm2) 和UVE (>8.94mL) 的特定值表明精子提取成功.

关键词:

微循环是一种微循环.亚精子缺血症 (Azospermia) 是一种不孕症不孕不育不孕不育不孕不育测试测试测试测试超声波学超声波学超声波学超声波学

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