Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

4.7K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
4.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Lewis-Acid Engineering with Neodymium Promoters as Synergistic Nd-Ni Dual Sites for Enhanced Urea Oxidation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

An end-to-end hybrid deep-learning approach for single-shot wavefront sensing and correction.

Nature communications·2026
Same author

<i>In vivo</i> fundus imaging and computational refocusing with a diffuser-based fundus camera.

Biophotonics discovery·2026
Same author

Dual-channel event microscopy for ultrafast biological imaging.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions.

Nature neuroscience·2026
Same author

Superiority of combined physiotherapeutic scoliosis-specific exercises in spinal deformity and quality of life of adolescents with idiopathic scoliosis: A meta-analysis of randomized controlled trials.

Journal of back and musculoskeletal rehabilitation·2026
Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026
Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026
Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026
Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026
Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026
Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026
查看所有相关文章

相关实验视频

Updated: Jun 20, 2025

A Guide to Build a Highly Inclined Swept Tile Microscope for Extended Field-of-view Single-molecule Imaging
08:13

A Guide to Build a Highly Inclined Swept Tile Microscope for Extended Field-of-view Single-molecule Imaging

Published on: April 8, 2019

17.5K

使用性照明的HiLo显微镜.

Guorong Hu1, Joseph Greene1, Jiabei Zhu1

  • 1Department of Electrical & Computer Engineering, Boston University , Boston, Massachusetts 02215, USA.

Biomedical optics express
|July 18, 2024
PubMed
概括
此摘要是机器生成的。

这项研究引入了可腐性HiLo显微镜,一种使用随机可腐性图案的新光学切割技术. 磁性HiLo显微镜增强了分散生物组织的成像,优于传统的基于斑点的方法.

更多相关视频

Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy
14:23

Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy

Published on: March 6, 2018

10.8K
Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline
09:14

Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline

Published on: September 13, 2022

2.5K

相关实验视频

Last Updated: Jun 20, 2025

A Guide to Build a Highly Inclined Swept Tile Microscope for Extended Field-of-view Single-molecule Imaging
08:13

A Guide to Build a Highly Inclined Swept Tile Microscope for Extended Field-of-view Single-molecule Imaging

Published on: April 8, 2019

17.5K
Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy
14:23

Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy

Published on: March 6, 2018

10.8K
Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline
09:14

Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline

Published on: September 13, 2022

2.5K

科学领域:

  • 生物医学成像技术 生物医学成像技术
  • 显微镜技术 显微镜技术
  • 光学工程是指光学工程.

背景情况:

  • HiLo显微镜结合了统一和结构化的照明,用于光学切割.
  • 随机斑点图案通常用于HiLo显微镜中的结构化照明.
  • 斑点图案提供了简单性和弹性,可以在生物组织中分散.

研究的目的:

  • 介绍和评估一种新的HiLo显微镜策略,使用随机的腐蚀模式.
  • 为了比较性HiLo显微镜与斑点HiLo显微镜的性能.
  • 为了证明可性HiLo用于成像分散生物样本的潜力.

主要方法:

  • 开发了一种HiLo显微镜系统,利用随机的腐蚀性图案,由现成的扩散器和低相干度的LED源生成.
  • 采用统一和结构化照明图像的计算组合.
  • 影像散射不同厚度的固定大脑部分 (100微米,300微米,500微米).

主要成果:

  • 实现了4.5微米的光学切割能力,具有20×0.75 NA的目标.
  • 与斑点HiLo显微镜相比,Caustic HiLo显微镜表现出更高的性能.
  • 展示了增强的光学切割和在分散的大脑组织中保存细特征.

结论:

  • 随机腐蚀模式为HiLo显微镜提供了一种新且有效的结构化照明策略.
  • 磁性HiLo显微镜在分散的生物样本中提供了改进的光学切割和特征保存.
  • 这种技术对各种生物医学成像应用具有前景.