认知投诉与UHR过渡相反相关
Mirvat Hamdan-Dumont1,2,3, Laurent Lecardeur4, Marine Habert1
1Centre Hospitalier Esquirol, Early Intervention Unit, Limoges 87000, France.
Schizophrenia research. Cognition
|July 18, 2024
概括
确定了经历精神病过渡的超高风险 (UHR) 青年. 自我报告的认知投诉可能表明这些处于风险的年轻人中对精神病过渡的保护因素.
科学领域:
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
- 神经科学是一个神经科学.
背景情况:
- 精神病的超高风险 (UHR) 是早期干预的关键时期.
- 识别过渡到精神病的预测因素对于及时的临床管理至关重要.
研究的目的:
- 研究临床决定因素对UHR年轻人六个月过渡到精神病的影响.
- 为了确定潜在的保护因素,防止精神病的过渡.
主要方法:
- 长度研究监测UHR年轻人超过六个月.
- 临床评估包括不寻常的思想内容和认知投诉.
- 使用逻辑等级和赔率比率 (OR) 来确定过渡预测因子的统计分析.
主要成果:
- 在39名UHR受试者中,有13人 (35.2%) 转变为精神病;没有一个非精神病对照 (p < 0.001).
- 不寻常的思想内容与精神病过渡有显著的关联 (OR 8.57).
- 自我报告的认知投诉显示与过渡的反向关联 (OR 0.13),表明有保护作用.
结论:
- 临床阶段和特定症状会影响UHR年轻人的精神病过渡.
- 自我报告的认知投诉可能作为一个保护性标记,保证进一步调查.
- 早期识别保护因素对于患精神病风险的UHR年轻人至关重要.
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