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食物蛋白诱导肠球炎综合征 (FPIES):超出了指导方针
Sohini Shah1, Rebecca Grohman1, Anna Nowak-Wegrzyn2,3
1Department of Pediatrics, Hassenfield Children's Hospital, Children's Hospital at Montefiore/Montefiore Medical Center, Bronx, New York.
Journal of food allergy
|July 18, 2024
概括
食物蛋白诱导肠球炎综合征 (FPIES) 是一种非IgE食物过敏,影响儿童和成人. 诊断是具有挑战性的,管理涉及避免食物和口服食物的挑战,在预防和诊断方面有未满足的需求.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 胃肠病学 胃肠病学
背景情况:
- 食物蛋白诱发性肠球炎综合征 (FPIES) 是一种非免疫球蛋白E (IgE) 介导的食物过敏.
- 它可以表现为严重的胃肠道症状,被认为是过敏紧急情况.
研究的目的:
- 审查FPIES的流行病学.
- 评估FPIES目前的诊断和管理方法.
主要方法:
- 2017年以来出版的同行评审文章的文献综述.
- 专注于研究FPIES流行病学,诊断和管理.
主要成果:
- 据估计,FPIES在美国影响了0.51-0.9%的儿童和0.22%的成年人.
- 常见的触发因素包括牛奶,麦,大米和梨;症状从吐到震惊.
- 由于缺乏生物标志物,诊断是具有挑战性的;管理涉及避免食物和口服食物的挑战.
结论:
- 在FPIES中迫切的未满足需求包括预防策略,改进的实验室诊断测试和加速耐受性发展的方法.
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