在哥伦比亚东部克里奥尔牛群中,牛白血病病毒的分子频率
Jeiczon Jaimes-Dueñez1, Eyner Goyeneche-Ortiz1, Marisol Tique-Oviedo1
1Grupo de Investigación en Ciencias Animales - GRICA, Facultad de Medicina Veterinaria y Zootecnia, Universidad Cooperativa de Colombia UCC, Bucaramanga, Colombia.
Veterinary and animal science
|July 18, 2024
概括
动物性牛白血病 (EBL) 影响着全球的牲畜. 这项研究在哥伦比亚克里奥尔牛群中发现了牛白血病病毒 (BLV) 基因型1,本地品种的感染率较低,这表明基因耐药性潜力.
科学领域:
- 兽医病毒学 兽医病毒学
- 传染性疾病 传染性疾病
- 动物遗传学动物遗传学
背景情况:
- 由牛白血病病毒 (BLV) 引起的动物性牛白血病 (EBL) 是一个重要的全球牲畜疾病.
- 哥伦比亚的克里奥尔牛品种面临着潜在的BLV暴露,需要了解感染动态和遗传因素.
研究的目的:
- 确定BLV感染的频率和分子特征在三个哥伦比亚克里奥尔牛品种中:奇诺桑坦德雷阿诺,卡萨纳雷诺和桑马丁内罗.
- 分析与BLV感染相关的流行病学因素及其在哥伦比亚东部的遗传特征.
主要方法:
- 2019年至2020年间,哥伦比亚东部四个省份的253头牛进行了横截面调查.
- 嵌套聚合酶链反应 (n-PCR) 针对BLV env基因进行前病毒检测,随后进行测序和遗传学分析.
- 流行病学变量的统计分析,包括年龄,部门,季节和总血清蛋白水平.
主要成果:
- 检测到总体BLV感染频率为26.48%,中华圣丹德拉诺品种的患病率最高 (35.1%).
- 感染频率与年龄,部门和季节有显著的关联 (P < 0.05).
- 独家鉴定了BLV基因型1,感染动物的总血清蛋白水平较高.
结论:
- 与引进品种相比,哥伦比亚克里奥尔牛品种的BLV感染频率较低,这表明潜在的内在遗传耐药性.
- 这些品种中BLV的流行病学和分子数据对于开发有针对性的控制策略和加强遗传耐药性计划至关重要.
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