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Updated: Jun 20, 2025

Author Spotlight: Epigenetic Modifications and Metabolic Rewiring as Targets for Cancer Therapy
07:20

Author Spotlight: Epigenetic Modifications and Metabolic Rewiring as Targets for Cancer Therapy

Published on: October 18, 2024

499

基因组脱甲基酶PHF8通过E2F1-SNAI1轴促进前列腺癌转移

Ze Wang1, Peng Tang1, Haiyang Xiao1

  • 1Department of Urology, Daping Hospital, Army Medical University, Chongqing, PR China.

The Journal of pathology
|July 18, 2024
PubMed
概括

PHF8蛋白通过上调SNAI1的调节,促进前列腺癌转移,这是表皮细胞转化为介质细胞转化 (EMT) 的关键因素. 向PHF8/E2F1-SNAI1通路为转移性前列腺癌提供了一个潜在的治疗策略.

关键词:
E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1在EMT中,EMT是EMT.PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8 PHF8在SNAI1上,你会看到SNAI1.转移 转移 转移 转移前列腺癌是前列腺癌.

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