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在雌性中,Drosophila melanogaster的精子会变得更加氧化

Cornelia Wetzker^1,2, Christin Froschauer¹, Christian Massino¹

¹Applied Zoology, Faculty of Biology, Technische Universität Dresden, 01062 Dresden, Germany.

The Journal of experimental biology

|July 18, 2024

概括

果精子的新陈代谢在储存期间会发生变化,利用糖解和氧化酸化. 意想不到的是,女性精子随着长时间的储存变得更加氧化,影响生殖策略.

科学领域:

生殖生物学生殖生物学
细胞的新陈代谢
进化生物学进化生物学

背景情况:

许多物种的精子存储长时间,经历代谢变化.
在精子储存期间,糖性代谢受到青,以减轻来自氧化酸化的氧化应激.
特定物种的代谢灵活性会影响精子功能和受精成功.

研究的目的:

调查Drosophila melanogaster的精子是否同时利用糖解和氧化酸化.
确定精子代谢在存储期间在两性之间如何发生变化.
探索观察到的代谢变化的进化影响.

主要方法:

在体外实验中抑制糖解和氧化酸化的实验.
多光子自发光终身成像 (FLIM) 的NAD (P) 和FAD.
分析不同储存时间的男性和女性储存器官的精子.

主要成果:

在体外抑制糖解会增加精子的氧化状态;抑制氧化酸化会增加糖解活性.
女性储存器官中的精子意外地比男性更具有氧化作用.
精子中的氧化酸化在雌性中随着储存时间的增加而增加.

结论:

德洛索菲拉黑虫的精子可以利用糖解和氧化酸化.
精子代谢表现出性别特异性差异和随着储存时间的变化.
这些代谢动态对精子活力和受精有着重要的进化影响.

关键词:

这种植物是Drosophila.这就是FAD FAD.飞行员飞行员的飞行员代谢过程中的代谢.它们是NADH和NADH.精子精子精子

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