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接受耐用左心室辅助器件的患者的死亡率,接受心室动脉动脉切除术

Patrick T Lynch¹, Alexandra Maloof¹, Anish Badjatiya²

¹Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA.

JACC. Clinical electrophysiology

|July 18, 2024

概括

在左心室辅助器件 (LVAD) 植入后,心室动脉冲动 (VT) 会增加死亡风险. 与单独的药物治疗相比,对静脉瘤的导管切除改善了LVAD患者的生存率.

科学领域:

心脏病学心脏病学
医疗器械医疗器械
电子生理学电子生理学

背景情况:

左心室辅助器件 (LVAD) 接收者面临着更高的风险心室低心率 (VT).
在LVAD患者中静脉瘤切除的有效性尚不清楚.

研究的目的:

调查LVAD植入后静脉瘤切除对患者存活时间的影响.
为了比较LVAD接受者与没有静脉瘤切除的生存率.

主要方法:

对575名LVAD接受者的回顾性队列研究 (2011年1月至2021年1月).
使用卡普兰-梅尔和考克斯模型分析静脉瘤发病率,发病时间和切除发生情况.
基于VT和废除状态的全因死亡率的比较.

主要成果:

植入后静脉瘤发生在53%的患者中,与一年内死亡率较高有关.
与单独的药物治疗相比,静脉瘤的导管切除改善了52%的生存率 (HR:0.48).
切除使死亡率与那些没有经历植入后静脉瘤的人相匹配.

结论:

在LVAD植入后一年内进行静脉治疗与较差的生存结果有关.
与医疗管理相比,导管切除可以改善LVAD接受者与静脉治疗的存活率.
需要进一步的前性研究来证实这些发现.

关键词:

晚期心力衰竭是什么意思导管切除导管切除导管切除导管切除左心室辅助装置的使用机械循环支持机械循环支持幸存率幸存率生存率腹腔动脉短心症是什么意思

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