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在人类遗传的DBR1缺乏症中,SARS-CoV-2脑干脑炎

Yi-Hao Chan1, Vanja Lundberg2,3, Jérémie Le Pen4

  • 1St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University , New York, NY, USA.

The Journal of experimental medicine
|July 18, 2024
PubMed
概括

遗传的RNA lariat-debranching酶1 (DBR1) 缺陷会损害脑干神经元的抗病毒免疫力. 这种遗传缺陷使个体易患严重的病毒脑干脑炎,包括来自SARS-CoV-2.

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