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直接观察将B细胞中的NFκBcRel与激活和终止其增殖程序相关联

Haripriya Vaidehi Narayanan1,2, Mark Y Xiang1,2, Yijia Chen1,2

  • 1Signaling Systems Laboratory, Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, CA 90095.

Proceedings of the National Academy of Sciences of the United States of America
|July 18, 2024
PubMed
概括

在NFκBcRel水平的自然变化控制B细胞增殖异质性. 高cRel表达最初促进B细胞扩张,但导致早期衰变,揭示了一个复杂的调节机制.

关键词:
B细胞的增殖 B细胞的增殖IκBε 负面的反.cRel光报道器的报道器细胞对细胞异质性的异质性直接观察是直接观察.

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