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Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...

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Updated: Jun 20, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

脑囊电疗法:一个模拟研究

Azam Ahmad Bakir¹, Donel M Martin, Abdulrahman Alduraywish

¹From the Smart Manufacturing Systems Research Group, University of Southampton Malaysia, Johor, Malaysia.

The journal of ECT

|July 18, 2024

概括

此摘要是机器生成的。

电治疗 (ECT) 脑模型显示,一个状囊会改变电场. 将电极放置在囊附近会改变电流通路,这可能会影响ECT的有效性和安全性.

更多相关视频

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Published on: April 11, 2019

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

Published on: June 7, 2016

相关实验视频

Last Updated: Jun 20, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Published on: April 11, 2019

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

Published on: June 7, 2016

科学领域:

神经科学是一个神经科学.
医疗成像医学成像
计算建模计算建模

背景情况:

电疗法 (ECT) 是严重神经精神疾病的重要治疗方法.
解剖学异常,如甲状腺囊,对ECT电场分布的影响尚不清楚.

研究的目的:

为了研究一个蜘蛛状囊如何影响电场 (E-field) 在ECT期间的分布.
为了比较患有囊的患者和假设无囊的患者的E场分布.

主要方法:

基于MRI扫描的有限元建模,一个患有左前额状囊的患者.
模拟了五个电极配置 (右侧单边,左侧单边,双额,双,左前右).
电子场分布与镜像健康脑组织模型的比较.

主要成果:

在囊附近观察到平均值和90百分比E场的显著差异,特别是在左下部和中部额头回转.
用离囊更近的电极组装 (左侧单边,比特孔口) 显示了E场分布中最明显的变化.

结论:

导电性状囊可以吸引电流,改变ECT通路,并可能影响治疗结果和安全性.
战略性的电极放置,可能远离囊,可以减轻对E场分布和临床结果的这些影响.