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Updated: Jun 20, 2025

A Functional Assay for Gap Junctional Examination; Electroporation of Adherent Cells on Indium-Tin Oxide
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对于EGF介导的酸-3,4,5-三酸盐生成和Akt信号传递,需要LCLAT1/LYCAT转移酶

Victoria Chan1,2, Cristina Camardi1,2, Kai Zhang2

  • 1Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.

Molecular biology of the cell
|July 18, 2024
PubMed
概括

LCLAT1酶对于受体氨酸激酶信号传递至关重要,包括EGF受体通路. 沉默LCLAT1降低了酸丁酸-3,4,5-三酸盐水平,并损害了Akt的激活,突出其在细胞生长和存活中的作用.

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