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用他类药物向胆固醇生物合成与三阴性乳腺癌中AKT抑制剂协同作用

Alissandra L Hillis1, Timothy D Martin2, Haley E Manchester3

  • 1Department of Pathology and Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Cancer research
|July 18, 2024
PubMed
概括

将AKT抑制剂与皮塔瓦斯塔丁结合使用显示出治疗三阴性乳腺癌 (TNBC) 的前景. 这种疗法针对胆固醇平衡,TNBC的脆弱性,导致癌细胞死亡,并提供了一个新的治疗策略.

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