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最近,大分子的细胞透量化的方法取得了进展

Nefeli Batistatou1, Joshua A Kritzer1

  • 1Department of Chemistry, Tufts University, Medford MA 02155, USA.

Current opinion in chemical biology
|July 18, 2024
PubMed
概括

药物开发人员面临的挑战是将大分子送到细胞内点. 本综述强调了测量细胞吸收和细胞质递送的新测试方法,这对于治疗成功至关重要.

关键词:
细胞透 细胞透药物输送是药物输送的过程.橄核酸的治疗药物类治疗药物 类治疗药物

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Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
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