智能手机辅助的光传感器用于可视化和定量检测多西环素和L-氨酸
Yuxin He1, Hecun Zou1, Song Zhou2
1College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Food chemistry
|July 18, 2024
概括
一个新的智能手机传感器使用欧/金属有机框架 (Eu/Zr-MOF) 来检测多西环素和L-氨酸. 这种传感器为食品和生物样本提供快速,灵敏和视觉分析.
科学领域:
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
- 纳米技术 纳米技术
背景情况:
- 金属有机框架 (MOF) 为传感应用提供了独特的特性.
- 基于欧的MOF表现出适合光检测的发光.
- 在食品安全和临床诊断方面,准确量化多西环素和L-阿基尼因至关重要.
研究的目的:
- 开发一种新的智能手机辅助光传感器,用于同时测定多西环素 (DOX) 和L-氨酸 (Arg).
- 调查基于光火和回收的传感机制.
- 为了验证传感器在现实世界食品和生物样本中的性能.
主要方法:
- 一个欧/金属有机框架 (Eu0.5/Zr0.5-MOF) 的合成.
- 使用内部波器效应 (IFE) 进行光火,使用DOX.
- 在Arg相互作用后使用光回收用于双分析物检测.
- 基于智能手机的光光谱学和视觉色度分析.
主要成果:
- 该Eu0.5/Zr0.5-MOF传感器展示了对DOX和Arg的敏感检测,具有广泛的线性范围 (DOX为0.05-80μg/mL,Arg为0.1-60μg/mL).
- 达到了低检测极限,DOX为2.07 ng/mL,为67.5 ng/mL.
- 成功监测了卵中的DOX和人血清样本中的Arg,显示出很好的恢复率.
- 观察到明显的光色彩变化,用于视觉定性评估.
结论:
- 开发的智能手机辅助的Eu0.5/Zr0.5-MOF传感器为DOX和Arg检测提供了一个快速,灵敏和视觉平台.
- 传感器分析真实样本的能力突出了其在食品和医疗保健领域现场监测的潜力.
- 这项工作为开发复杂矩阵的基于MOF的光传感器提供了一种多功能方法.
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