单细胞蛋白:克服技术和生物挑战,实现更好的工业化
Lijuan Ye1, Biljana Bogicevic1, Christoph J Bolten1
1Nestlé Research, Lausanne, Switzerland.
Current opinion in biotechnology
|July 18, 2024
概括
单细胞蛋白 (SCP) 提供可持续的食品解决方案,但面临成本和规模挑战. 本研究分析了制造工艺,以确定成本高效的大规模SCP生产的关键创新.
科学领域:
- 生物技术是生物技术.
- 可持续的粮食生产可持续的粮食生产
- 工业微生物学 工业微生物学
背景情况:
- 几十年来,从微生物发酵中生产单细胞蛋白 (SCP) 已经存在了几十年,早期的商业例子包括Pruteen (动物料) 和Quorn® (人类营养).
- SCP因其有潜力为日益增长的全球人口提供可持续的粮食安全而受到认可.
- 目前SCP应用的局限性源于高的生产成本和实现大规模可用性的挑战.
研究的目的:
- 审查目前单细胞蛋白质制造的最新技术状况.
- 为各种SCP生产场景提供全面的技术经济和生命周期评估见解.
- 确定优化SCP生产效率和成本效益的关键技术挑战和机会.
主要方法:
- 审查关于单细胞蛋白 (SCP) 制造工艺的现有文献.
- 对不同SCP生产路线的技术经济评估 (TEA) 的分析.
- 对生命周期评估 (LCA) 的评估,以了解环境影响.
- 确定关键的流程组件和创新优先事项.
主要成果:
- 该研究确定了主要SCP生产场景中的关键技术"热点"和挑战.
- 技术经济和生命周期评估突出了流程优化的领域.
- 确定了影响成本效益和大规模生产可行性的关键因素.
结论:
- 优化制造工艺对于克服单细胞蛋白 (SCP) 生产成本和规模限制至关重要.
- 针对关键过程组件的有针对性的创新可以提高可负担性和生产力.
- 需要进一步的研究和开发,才能充分发挥SCP作为可持续食物来源的潜力.
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