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人类角膜上皮细胞中TRPV4的激活促进了膜粘素的产生

Yoshiyuki Yamada1, Yuko Terada2, Rie Yamanaka3

  • 1Department of Food and Nutritional Sciences, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

Biochemical and biophysical research communications
|July 18, 2024
PubMed
概括

研究人员在角膜细胞中确定了短暂受体潜在化物4 (TRPV4). 激活TRPV4会增加粘素的表达,这对膜的稳定性至关重要,这表明了新的干眼治疗标.

关键词:
化学感知受体受体是化学感知受体.角膜上皮细胞 角膜上皮细胞眼睛 眼睛 眼睛 眼睛粘真菌 粘真菌 粘真菌在 TRPV4 中.

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The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...