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Updated: Aug 10, 2026

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Published on: January 29, 2015

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在小鼠中Dync1h1的患者特异突变会导致大脑和行为缺陷

Raddy L Ramos1, Maider Michelena Beltran De Heredia2, Yongwei Zhang3

  • 1Department of Biomedical Sciences, New York Institute of Technology, College of Osteopathic Medicine, Riland Academic Health Center, Room 26, Old Westbury, NY 11568, United States of America.

Neurobiology of disease
|July 18, 2024
PubMed
概括

一种具有DYNC1H1突变 (P3018S) 的新老鼠模型表现出运动缺陷和神经元迁移问题,反映了人类的状况. 这突出了细胞质二烯的突出.

关键词:
神经元的异常定位异常自闭症谱系障碍 (ASD) 是一种皮层层特定的转录因子在De novo dynein重链突变中.不同类型的世界 (Heterotopia)神经元迁移缺陷是一种神经元迁移缺陷.

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