摩洛哥的绝经后骨质疏松症的流行:系统性审查和元分析
Anass Kherrab1, Hamza Toufik2, Mirieme Ghazi3
1Department of Rheumatology, Avicenne Military Hospital, Cadi Ayyad University, Marrakesh, Morocco. anasskherrab@gmail.com.
Archives of osteoporosis
|July 18, 2024
概括
绝经后的骨质疏松症影响摩洛哥32%的妇女,其患病率与工业化国家相当. 这一系统性审查强调了这种疾病.
科学领域:
- 骨健康和骨质疏松症研究
- 公共卫生流行病学 流行病学
- 系统性审查和元分析
背景情况:
- 摩洛哥的绝经后骨质疏松症管理指南要求更新流行数据.
- 这项研究解决了对摩洛哥绝经后妇女骨质疏松症的最新流行病学信息的需求.
研究的目的:
- 使用可用的文献数据,估计摩洛哥的绝经后骨质疏松症的流行率.
- 为更新管理绝经后骨质疏松症的国家建议提供信息.
主要方法:
- 在Medline/PubMed,Scopus和Embase (2000-2024) 的系统文献搜索.
- 包括摩洛哥绝经后妇女的观察性研究;数据提取和偏见风险评估 (Joanna Briggs研究所).
- 使用 Stata 进行异质性评估 (I2 测试) 和元回归分析时间趋势的元分析.
主要成果:
- 分析了包括5097名女性在内的17项研究;绝经后骨质疏松症的综合患病率为32% (95%CI 28-36).
- 观察到显著的异质性 (I2=89.67%);在2006-2012年 (36%) 的流行率高于2013-2019年 (27%).
- 超回归表明,当考虑低偏差研究时,随着时间的推移,流行率略有而非显著下降.
结论:
- 绝经后的骨质疏松症在摩洛哥非常普遍.
- 观察到的患病率与工业化国家发现的患病率一致.
- 这些发现支持需要继续关注摩洛哥的骨质疏松症管理.
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