探索患者的观点,以优化实施一种用于预防心房的生物疗法
Chloé Smith1, Manoj M Lalu2,3,4, Darryl R Davis1,2
1Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada.
CJC open
|July 19, 2024
概括
患者的观点对于采用新疗法至关重要. 这项研究发现,为患者提供有关术后心房 (AF) 细胞外囊泡 (EV) 治疗的教育,增加了他们的理解和接受,大多数人都愿意参加临床试验.
科学领域:
- 生物医学研究的研究.
- 再生医学是一种再生医学.
- 患者为中心的结果.
背景情况:
- 患者的接受是新型治疗转换的关键.
- 细胞外囊泡 (EVs) 显示出作为手术后心房动 (AF) 的生物治疗方法的希望.
- 了解患者对EV治疗的态度至关重要.
研究的目的:
- 评估患者接受EV治疗以预防术后AF的可接受性.
- 确定患者对EV治疗的态度和信息需求.
- 探索影响患者接受这种新干预的因素.
主要方法:
- 患者参与了预先录制的演讲,虚拟焦点小组和调查.
- 在教育干预之前和之后进行了评估.
- 收集关于理解,态度和愿意参加试验的数据.
主要成果:
- 最初对手术后的AF和生物疗法不熟悉是很常见的.
- 教育干预显著改善了参与者的理解和理解能力.
- 大多数参与者表现出对EV治疗的接受度增加,并愿意参加临床试验.
- 关键问题包括风险,副作用,来源,剂量和艾滋病毒/过敏风险.
结论:
- 患者教育和解决问题对于接受术后AF的EV治疗至关重要.
- 涉及患者的护理圈可以提高治疗的接受度.
- 以患者为中心的方法加速了像EVs这样的新疗法的临床转化.
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