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标志着骨肌肉免疫微环境对萨尔科佩尼亚:从转录组分析和组织学验证的见解

Linhui Shen1, Yuan Zong2, Jiawen Zhao2

  • 1Department of Geriatrics, Ruijin hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Frontiers in immunology
|July 19, 2024
PubMed
概括

肉症涉及与年龄相关的肌肉损失,由炎症驱动. 这项研究揭示了sarcopenic肌肉中明显的免疫细胞变化,突出了巨细胞作为这种疾病的潜在治疗点.

关键词:
细胞通信的细胞通信.免疫微观环境 免疫微环境这是一种炎症炎症炎症炎症.这种类型的麻症是sarcopenia.一个单细胞RNA测序.这是骨肌肉的骨架肌肉.转录组学 转录组学是指转录组学.

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Skeletal muscle cells, also called muscle fibers, are distinctly elongated, multi-nucleated, slender biological units. They are packed with specialized structures designed to facilitate their primary function, which is contraction.
The muscle sarcolemma is a plasma membrane enclosing each muscle cell that conducts electrical signals called action potentials. The sarcolemma extends into the cell to form T-tubules, ensuring the neural impulses are uniformly distributed across the entire muscle...