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Updated: Jun 20, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

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瘤性NOVA1表达失调乳腺癌的替代拼接

Daniel F Moakley1,2, Chaolin Zhang1,2

  • 1Department of Systems Biology, Columbia University, New York, NY 10032, USA.

bioRxiv : the preprint server for biology
|July 19, 2024
PubMed
概括

神经瘤室内抗原1 (NOVA1) 在乳腺癌中驱动神经元类拼接,特别是Luminal A瘤. 高NOVA1表达与更差的预后相关,表明潜在的致癌作用.

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