决策塑造了的腹前皮层内的动态区域间沟通.
Frederic M Stoll1,2, Peter H Rudebeck1
1Nash Family Department of Neuroscience, Lipschultz Center for Cognitive Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
的腹前皮层区域在决策过程中动态相互作用. 特定区域整合信息,揭示认知控制所必需的沟通模式.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 灵长类大脑研究研究
背景情况:
- 的腹前皮层 (VFC) 包含了参与决策的相互连接区域.
- 在决策过程中,在VFC内部理解动态的区域间通信是有限的.
研究的目的:
- 在决策任务期间调查解剖学定义的VFC子部分之间的功能相互作用.
- 阐明神经通信模式如何支持决策中的自适应控制.
主要方法:
- 分析从八个VFC分区的单个神经元活动,在做一个概率选择任务.
- 评估VFC区域之间的功能连接和信息流.
主要成果:
- 刺激开始和奖励交付在全球范围内增强了整个VFC的沟通.
- 区域间的通信是时间特定的,利用独特的活动子空间,并取决于决策变量.
- 区域12l和12o表现出高度的连接性,主要是接收信息,这表明了整合作用.
结论:
- 这项研究揭示了VFC在决策过程中的特定,动态的区域间通信模式.
- 功能连接模式表明,VFC子部门在信息处理和集成方面具有不同的角色.
- 这些发现增强了我们对适应性决策控制背后的神经机制的理解.
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