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用低剂量激光循环塑性治疗恶性玻璃眼:为期一年的多中心前性非比较性研究
Hai-Shuang Lin1, Xiao-Ping Xu2, Xuan-Li Zheng1
1Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
International journal of ophthalmology
|July 19, 2024
概括
低剂量激光循环整形 (LCP) 在恶性绿眼病患者中有效地改造了前腔,在一年内显著降低了眼内压力和药物需求. 虽然最初的成功率很高,但由于一些复发,观察到12个月成功率为64.3%.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 手术干预 手术干预
背景情况:
- 恶性玻璃眼是一种严重的闭角玻璃眼的形式.
- 改革前腔对于管理恶性绿眼病至关重要.
- 低剂量激光循环整形 (LCP) 是一种潜在的治疗方式.
研究的目的:
- 评估低剂量激光循环形成术 (LCP) 一年临床结果.
- 评估LCP在患有恶性玻璃眼的患者中的疗效和安全性.
主要方法:
- 前性,多中心,非比较性临床研究.
- 34个患有恶性绿眼瘤的眼睛接受了LCP.
- 随访包括IOP,药物使用,前腔深度和1周后的并发症以及1,3,6,12个月的并发症.
主要成果:
- 在12个月内,平均内血压从36.1±11.5 mmHg降低到17.4±6.7 mmHg (P<0.001).
- 青光眼药物的使用量显著下降.
- 最初的解剖成功率为94.1%,在考虑到复发后,12个月的成功率为64.3%.
- 并发症包括前侧突,胸腔/眼脱落和低.
结论:
- 低剂量激光循环整形 (LCP) 是一种简单,安全和有效的程序.
- 在恶性玻璃眼患者中,LCP成功地改革了前腔.
- 由于潜在的复发,长期疗效需要监测.
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