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新生儿多系统炎症综合征 (MIS-N):一个更新的系统性审查

Divya Muthiah¹, Ming Chan², Yue Wey Low¹

¹Ministry of Health Holdings, Singapore, Singapore.

Frontiers in pediatrics

|July 19, 2024

概括

新生儿多系统炎症综合征 (MIS-N) 通常会出现心肺呼吸系统问题. 对于怀疑母体COVID-19暴露的患病新生儿,早期考虑MIS-N至关重要.

科学领域:

新生儿科学新生儿科学
儿童传染病儿童传染病
关键护理医学关键护理医学

背景情况:

新生儿多系统炎症综合征 (MIS-N) 是一种罕见但严重的疾病.
了解其临床特征和结果对于及时诊断和管理至关重要.

研究的目的:

系统地审查和更新诊断出MIS-N.的新生儿的临床特征和结果.
提供有关MIS-N.N.的当前知识的全面摘要.

主要方法:

在主要数据库 (PubMed,MEDLINE,EMBASE,CNKI,WHO COVID-19) 中进行了系统的文献搜索,搜索了2019年12月至2023年6月期间发表的研究.
通过参考列表,谷歌学者和预印服务器确定了其他研究. 评估了方法质量.

主要成果:

包括35项涉及201名患有MIS-N的新生儿的研究. 71.6%的人出现呼吸困难,55.7%的人患有心脏病.
在现有数据的78.7%的病例中,在第三个三个月内发现了母亲的COVID-19感染. 死亡率为5.0%,死亡率为5.0%.

结论:

在涉及多器官系统的新生儿中,应该怀疑MIS-N,特别是心肺呼吸系统功能障碍.
在怀孕期间有母亲COVID-19感染史的新生儿中,考虑MIS-N是很重要的.

关键词:

在 COVID-19 疫情中,心血管呼吸系统功能障碍多系统炎症综合征多系统炎症综合征新生儿们的新生儿怀孕怀孕怀孕怀孕怀孕

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