TG/HDL-C比率与NAFLD患者中心血管疾病的风险和严重程度有关:一个病例对照研究
Biwei Cheng1,2, Yumeng Yi1,2, Mingtai Chen1
1Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
甘油三与高密度脂蛋白胆固醇 (TG/HDL-C) 的比率是非酒精性脂肪肝病 (NAFLD) 患者冠状动脉心脏病 (CHD) 的重要危险因素. 较高的TG/HDL-C比率与心脏病风险和严重程度的增加相关,用根西尼分数来衡量.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 代谢综合征是代谢综合征的一种.
背景情况:
- 在全球范围内,非酒精性脂肪性肝病 (NAFLD) 的患病率越来越高.
- NAFLD与心血管疾病风险增加有关,包括冠状动脉心脏病 (CHD).
- 甘油三与高密度脂蛋白胆固醇 (TG/HDL-C) 的比率正在成为心血管风险的潜在标志物.
研究的目的:
- 调查TG/HDL-C比率与NAFLD患者心脏病风险之间的关联.
- 评估TG/HDL-C比率与NAFLD患者冠状动脉样硬化的严重程度之间的相关性.
主要方法:
- 一项对278名患有NAFLD和胸痛的患者进行的回顾性研究.
- 计算TG/HDL-C比率和冠状动脉血管图的性能.
- 使用Gensini评分对冠状动脉狭窄的严重程度进行量化.
主要成果:
- 在NAFLD患者中,TG/HDL-C比被确定为心脏病的独立风险因素 (OR 1.791).
- 增加的TG/HDL-C比率与显著更高的心脏病风险相关 (T2:OR 2.17,T3:OR 2.84).
- 每增加1个单位的TG/HDL-C比率与Gensini分数增加7.75个点相关.
结论:
- 在NAFLD患者中,TG/HDL-C比率与心脏病风险正相关.
- TG/HDL-C比率有效地反映了这一群体冠状动脉样硬化的严重程度.
更多相关视频
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
07:12Author Spotlight: Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment
Published on: June 2, 2023
相关概念视频
Hazard Ratio
For example, in a clinical trial...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Hypothesis Test for Test of Independence
H0: The two variables (factors)...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Relative Risk
