胃肠道手术中的手术部位感染:患病率估计,危险因素和细菌学概况
Bargavi K1, Secunda R2, Saravanan J2
1Medicine, Stanley Medical College, Chennai, IND.
Cureus
|July 19, 2024
概括
手术部位感染 (SSIs) 影响了24%的胃肠道手术患者,像大肠杆菌这样的グラム阴性细菌很常见. 识别风险因素和抗菌素耐药性模式对于有效的医院抗生素政策至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 手术感染 手术感染
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 手术部位感染 (SSIs) 是不良手术结果的主要原因之一.
- 了解当地的感染模式对于有效的医院感染控制计划至关重要.
- 抗生素耐药性增加使SSI管理复杂化.
研究的目的:
- 为了确定SSI在胃肠道外科手术中的患病率.
- 识别与SSI发展相关的风险因素.
- 识别最常见的导致SSI的微生物及其对抗菌素的敏感性.
主要方法:
- 在两个月内进行了一项分析性横截面研究.
- 包括接受选择性手术,术后停留时间至少为7天的患者.
- 通过修改的CDC标准来诊断SSI;进行了微生物鉴定和抗菌素敏感性测试.
主要成果:
- 该研究发现SSI率为24% (50名患者中12名).
- 确定的危险因素包括年龄,BMI,伤口类别,ASA分数,高白细胞计数和手术持续时间.
- 大肠杆菌是最常见的病原体 (35.7%),其中格拉姆阴性生物和多抗药菌株占主导地位. 发现了扩展光谱β-乳糖酶 (ESBL) 的产生.
结论:
- 胃肠道外科手术中的SSI率为24%.
- 包括ESBL生产者在内的流行多药耐药格拉姆阴性生物体构成了重大挑战.
- 了解敏感性和耐药性模式对于制定有效的抗生素预防政策至关重要.
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