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中链甘油和黄油对脂质谱的影响
Thanh D Hoang1, Jennifer S Hatfield1, Karl Nadolsky2
1Endocrinology, Walter Reed National Military Medical Center, Bethesda, USA.
Cureus
|July 19, 2024
概括
在12周后,将中链甘油油 (MCT) 油和黄油添加到咖啡中并没有显著改变健康成年人的脂质特征或冠状动脉疾病风险因素. 需要进一步的研究来证实这种流行的饮料组合的安全性和效果.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢研究 代谢研究
背景情况:
- 黄油咖啡是咖啡与黄油和中链甘油油 (MCT) 油的混合物,被认为是一种健康的能量增强饮料,特别是在年轻,健康的人群中.
- 人们担心黄油咖啡中和脂肪对心血管健康标志物的影响,包括脂质样本和其他冠状动脉疾病风险因素.
研究的目的:
- 调查与黄油和MCT油一起饮用咖啡对脂质特征的影响,重点关注阿波利波蛋白B (ApoB),LDL胆固醇 (LDL-C) 和HDL胆固醇 (HDL-C).
- 评估对其他冠状动脉疾病风险因素的影响:体重指数 (BMI),血压 (BP),禁食血糖,HbA1c和高灵敏性C反应蛋白 (hs-CRP).
主要方法:
- 一项前性研究涉及60名健康成年人,随机分为两组:一组消费普通咖啡,另一组咖啡含黄油和MCT油.
- 主要结局:ApoB水平的变化. 其次性结局包括非HDL-C,LDL-C,HDL-C,甘油三,BMI,BP,腰围,禁食血糖,HbA1c和hs-CRP.
- 测量是在基线和12周干预期后进行的,结果使用曼-惠特尼U测试进行分析.
主要成果:
- 12周后,在ApoB,LDL-C,HDL-C,甘油三,BMI,BP或hs-CRP水平方面,对照组和实验组之间没有观察到统计学上显著的差异.
- 虽然一些值,如HDL-C和甘油三,在实验组中呈现改善趋势,但在5%的水平上,这些值没有达到统计学意义.
- 参与者的坚持是中等的,在60名受试者中,有41人完成了研究.
结论:
- 在12周的时间内,将MCT油和黄油添加到咖啡中似乎对健康的成年人来说是安全的,对关键脂质概况或心血管风险标志物没有不良影响.
- 这项研究表明,黄油咖啡可能不会对这种人群的短期脂质特征产生负面影响.
- 建议采用更大的样本大小和更长的研究持续时间,以最终验证这些发现并探索潜在的长期影响.
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