儿科自身移植中肠道营养疗法:一种描述性队列研究
Andressa Florencio da Silva1,2, Vera Lucia Bosa2,3, Estela Beatriz Behling1,2
1Nutrition Service. Multiprofessional Health Residency Program: Onco-Hematology, Porto Alegre Clinical Hospital, Porto Alegre, Brazil.
Nutrition and cancer
|July 19, 2024
概括
早期的肠道营养对于儿科造血干细胞移植患者至关重要. 然而,在治疗期间,营养状况下降,突出需要改进肠道营养方案.
科学领域:
- 儿科血液学 儿科血液学
- 移植营养 移植营养 移植营养
- 胃肠病学 胃肠病学
背景情况:
- 儿童造血干细胞移植 (HSCT) 需要量身定制的营养支持.
- 早期肠道营养 (EN) 已被公认为其在儿科HSCT中的好处.
- 这项研究考察了自主HSCT接受者的EN实践.
研究的目的:
- 分析肠道营养疗法的利用和影响,在接受自主HSCT的儿科患者中.
- 在移植后早期评估营养和临床变量.
- 识别EN配方选择的趋势和对腹腔营养的需求.
主要方法:
- 使用电子病历进行描述性队列研究 (2017-2022年).
- 包括接受EN.接受自主HSCT的儿科患者.
- 在四个时间点对营养,临床和生化数据的评估:第0天,第5天,第10天和第15天.
主要成果:
- 包括50名患者;鼻管通常在移植前放置 (D-4),并开始食 (D-3).
- 配方类型从Normocaloric聚合物转变为 hypocaloric半元素 D+10 由于腹和粘膜炎增加.
- 35%的患者在D+15时需要腹腔营养,并且从入院到出院的整体营养状况恶化.
结论:
- 早期的EN启动与既定实践和文献建议保持一致.
- 恶化的临床状况 (腹,粘膜炎) 需要调整配方,并可能导致依赖腹腔营养.
- 在儿科HSCT中开发EN的特定协议和指导方针对于优化患者的治疗结果至关重要.
相关概念视频
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
103
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
103
Enteral Nutrition I: Orogastric and Nasogastric Feeding
240
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
240
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
120
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
120
Bone Marrow Sampling and Transplants
321
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
321


