对乌干达渔民实施增强的口服预暴露预防 (PrEP):试点干预结果
Laura M Bogart1,2, William Musoke3, Christopher Semei Mukama3
1RAND Corporation, 1776 Main Street, P.O. Box 2138, Santa Monica, CA, 90407-2138, USA. lbogart@rand.org.
AIDS and behavior
|July 19, 2024
概括
基于社区的策略显著改善了维多利亚湖移动渔民的暴露前预防 (PrEP) 吸收和坚持. 这些干预措施减少了耻辱和误解,增强了难以接触的人群中艾滋病毒预防.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 实施科学 实施科学
背景情况:
- 移动人口,如渔民,呈现高艾滋病毒发病率和流行率.
- 对这些社区来说,获得医疗保健和持续参与艾滋病毒预防方法,如暴露前预防 (PrEP) 仍然是一个挑战.
研究的目的:
- 试点实施旨在提高渔民社区内PrEP吸收和遵守的实施策略.
- 评估基于社区的干预措施在改善移动人口艾滋病毒预防结果方面的有效性.
主要方法:
- 在2021年9月至2022年2月期间,在乌干达维多利亚湖的两个渔民社区进行了一项试点研究.
- 实施策略包括PrEP坚持支持者,社区研讨会解决污名和误解,并定期检查电话与补充提醒.
- 数据收集涉及PrEP医疗记录 (干预前6个月至干预后6个月),以及对使用者,支持者和关键合作伙伴的定性访谈.
主要成果:
- 在干预期间,与干预前时期 (84.5%) 相比,PrEP启动率显著增加 (96.5%).
- 在干预期间,在开始后6个月的PrEP持久性 (47.9%对6.7%) 和80%的药物覆盖率 (35.9%对0%) 显著更高.
- 定性发现表明,这些策略减少了耻辱和误解,从而促进了PrEP的使用.
结论:
- 加强社区 PrEP 实施促进了支持性环境,大大改善了 PrEP 在移动人口中使用的情况,这些人获得医疗保健的机会有限.
- 该干预措施证明了提高PrEP启动,持续性和覆盖率的成本效益.
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