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CD5删除增强了采用T细胞疗法的抗瘤活性

Ruchi P Patel1,2,3, Guido Ghilardi1,2,3, Yunlin Zhang1,2,3

  • 1Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.

Science immunology
|July 19, 2024
PubMed
概括

删除CD5增强了仿真抗原受体 (CAR) T细胞治疗对抗癌症的有效性. CD5淘汰会促进CAR T细胞的功能,扩张和持久性,在临床前模型中改善抗瘤效果.

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