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Updated: Jun 20, 2025

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为了通过Candida glabrata Pdr1转录因子进行转录激活,需要重叠的协激活器功能

Thomas P Conway1, Lucia Simonicova1, W Scott Moye-Rowley1

  • 1Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

Genetics
|July 19, 2024
PubMed
概括

在Pdr1转录因子中获得功能的突变驱动了Candida glabrata中的醇耐药性. SWI/SNF和SAGA复合体是Pdr1-介导基因转录的必不可少的联合激活剂,对抗性至关重要.

关键词:
在Candida glabrata的研究中.药物耐药性 耐药性 药物耐药性致病性酵母酵母是一种病原性酵母.转录 转录 是一种转录.

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