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Updated: Jun 24, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

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在ZIF-8纳米粒子中捕获血红蛋白 (Hb) 的一种新的PEG介导方法:平衡晶体结构,Hb含量和功能

Clara Coll-Satue1, Marta Rubio-Huertas1, Aurelie Ducrot1

  • 1Department of Health Technology, Center for Nanomedicine and Theranostics, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800 Kgs. Lyngby, Denmark.

Biomaterials advances
|July 19, 2024
PubMed
概括

研究人员使用聚乙烯糖醇 (PEG) 开发了新的血红蛋白纳米粒子 (Hb@ZIF-8 NPs),用于输送氧气. 这些PEG稳定Hb纳米颗粒在危急情况下为输血提供了一个有希望的替代方案.

关键词:
血液的替代品 血液的替代品血液中的血球蛋白.基于血红蛋白的氧气载体是以血红蛋白为基础的.金属有机框架的框架.这里是ZIF-8的位置.

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Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b10:20

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Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
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Globular and Fibrous Proteins

Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities.
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...