相关实验视频

Updated: Jun 20, 2025

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells
15:28

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells

Published on: October 1, 2010

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开发共价化学遗传K2P通道激活剂

Parker E Deal1, Haerim Lee2, Abhisek Mondal2

  • 1Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA.

Cell chemical biology
|July 19, 2024
PubMed
概括

研究人员开发了CATKLAMP,这是一种化学遗传方法,可以不可逆转地激活 (K2P) 通道. 这一新策略允许精确控制神经元刺激性,并为研究K2P通道功能和开发新疗法打开了道路.

关键词:
K (((2P) 的通道道.ML33535 没有使用.这就是TREK-1的特点.在X射线晶体学.化学遗传学 化学遗传学电力生理学 电力生理学通道是一种通道.

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