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Updated: Jun 20, 2025

The Soft Agar Colony Formation Assay
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哺乳动物SWI/SNF复合体活性调节POU2F3并构成小细胞肺癌中可向的依赖性

Leslie Duplaquet1, Kevin So2, Alexander W Ying3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.

Cancer cell
|July 19, 2024
PubMed
概括

POU2F3阳性小细胞肺癌 (SCLC) 依赖mSWI/SNF复合体进行生长. 抑制这些复合物,包括非正规的BAF (ncBAF),表明作为这种SCLC亚型的新治疗策略具有前途.

关键词:
这就是BRD9的原因.在FHD-286中使用.在FHD-60中使用.这是OCA-T1T1的OCA-T1T1.这就是OCA-T2的原因.在POU2F3F3中.在SMARCD1中,它被定义为SMARCD1.mSWI/SNF 这两种类型.神经内分泌神经内分泌小细胞肺癌是一种小细胞肺癌.

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