身体活动和环境颗粒物之间的相互作用对中国社区生活的老年人认知功能的影响很大
Junzhe Li1, Qiang Liu1, Ziwei Tian1
1Department of Epidemiology and Health Statistics, Center for Big Data and Population Health of IHM, School of Public Health, Anhui Medical University, Hefei 230032, Anhui, China.
Journal of affective disorders
|July 19, 2024
概括
当空气污染 (PMs) 高时,体力活动 (PA) 可能会使老年人的认知功能恶化. 在受污染的环境中建议使用低水平的PA,以保护认知健康.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 身体活动 (PA) 和环境颗粒物 (PMs) 暴露对认知功能的相互作用仍未得到充分研究.
- 老年人认知能力下降是一个重大的公共卫生问题.
研究的目的:
- 调查体力活动和颗粒物暴露对中国社区老年人的认知功能的影响.
主要方法:
- 利用了3937名老年人的数据,通过迷你精神状态检查 (MMSE) 评估认知能力.
- 采用国际体力活动问卷和来自中国高空气污染物 (CHAP) 数据集的颗粒物数据收集的体力活动数据.
- 使用线性回归模型,交互图和贝叶斯内核机器回归 (BKMR) 来分析和可视化交互.
主要成果:
- 颗粒物暴露 (PM1,PM2.5,PM10) 与MMSE得分有负相关性.
- 身体活动与MMSE得分有积极的关联,但这种关联因PM水平较高而减弱.
- 相互作用分析显示,更高的PA水平加剧了PMs对认知的负面影响,并且确定了这些相互作用的可辨认的值.
结论:
- 在高 PM 暴露期间,应适度体力活动,以保护老年人的认知功能.
- 在受污染的环境中,低水平的体力活动对保持认知健康可能是有益的.
- 需要进一步的研究,包括实验和队列研究,以验证这些发现.
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