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Updated: Jun 20, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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Published on: June 8, 2022

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伪不可逆转的抑制引起了斯芬戈-1-酸盐受体1抗剂的持续有效性

Yuya Maruyama1,2,3, Yusuke Ohsawa3, Takayuki Suzuki3

  • 1Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.

Nature communications
|July 19, 2024
PubMed
概括

一种新的化合物,KSI-6666,作为一种伪不可逆转的氨酸1-酸盐受体1 (S1PR1) 抗剂. 这种新的机制导致持续抑制炎症,提供了一个有前途的治疗方法.

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