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以分子动力学为指导的BGM0504优化增强了对抗糖尿病和肥胖的双重目标激进作用

Jiandong Yuan1, Wenlang Liu2, Xiaohui Jiang3

  • 1BrightGene Bio-Medical Technology Co., Ltd, Suzhou, 215000, People's Republic of China. jiandong_yuan@bright-gene.com.

Scientific reports
|July 19, 2024
PubMed
概括

研究人员优化了一种双重GLP-1R/GIPR激动剂,用于2型糖尿病和肥胖. 新的,BGM0504,显示显著增强的活性和疗效比提尔泽帕提德,同时保持长半衰期.

关键词:
抗激素的激进分子.糖尿病和肥胖症 糖尿病和肥胖在 GLP-1R/GIPR 中.分子动力学分子动力学纳什·纳什 (Nash Nash) 是一个名为纳什的城市.

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