质母细胞瘤蛋白质的突变不会破坏表位表现和识别,保持特定的CD8 T细胞免疫反应潜力

Renata Fioravanti Tarabini1, Gustavo Fioravanti Vieira2,3, Maurício Menegatti Rigo4,5

  • 1Laboratory of Clinical and Experimental Immunology, Infant Center, School of Health Science, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.

Scientific reports
|July 19, 2024
PubMed
概括

这项研究调查了质母细胞瘤突变如何影响T细胞反应. 研究人员确定了特定的TP53突变,这些突变改变了T细胞表皮图表的呈现,为新的质母细胞瘤免疫疗法提供了潜在的标.

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