饮食维生素A摄入量与心脏代谢多病症风险之间的关联
Yudi Tang1, Yao Xiao2,3,4, Fen Yang1
1School of Nursing, Hubei University of Chinese Medicine, Wuhan, China.
Scientific reports
|July 19, 2024
概括
更高的饮食维生素A摄入量,包括视网醇和β-胡卜素,与降低患心脏代谢多病症 (CMM) 的风险有关. 这种保护作用在患有心血管疾病的个体中尤为明显.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 单个心脏代谢疾病和维生素A已经建立了联系.
- 饮食维生素A与心脏代谢多病症 (CMM) 之间的关联仍未得到研究.
研究的目的:
- 研究饮食维生素A摄入量与患CMM的风险之间的关系.
- 分析不同维生素A来源对CMM风险的影响.
主要方法:
- 利用来自中国健康和营养调查 (CHNS) 的13,603名成年人 (1997-2015) 的数据.
- 通过24小时召回和家庭食品库存评估饮食摄入量.
- 定义CMM为至少两种心脏代谢疾病的发病,随访时间中位数为9.0年.
主要成果:
- 较高的维生素A摄入量显著降低了CMM风险 (Q1 vs Q5 HR 0.66).
- 贝塔胡卜素和视网醇摄入量都显示出与CMM风险的负相关性.
- 在视网醇摄入量和CMM风险之间观察到L形关系 (p非线性<0.001).
- 对高血压,心血管疾病,中风和糖尿病也发现了负面关联.
结论:
- 饮食中的维生素A摄入量与CMM风险有负面关联.
- 维生素A对CMM的保护作用在心血管疾病患者中更为明显.
- 雷丁醇摄入量表现出与CMM风险的L形关联.
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