环境和神经发育因素导致青少年精神疾病
Sarah Whittle1,2, Lu Zhang3,4, Divyangana Rakesh5
1Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia. swhittle@unimelb.edu.au.
概括
早期的生活社会环境和大脑发育显著影响年轻人的精神疾病. 研究表明,大脑的变化可以影响社会因素如何影响内化症状,指导未来的研究方向.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 年轻人的精神疾病是由社会环境和神经发育变化之间的复杂相互作用引起的.
- 现有的理论提出神经发育变化中介或中等社会环境对精神疾病的影响.
- 目前的证据虽然有限,但支持特定的神经发育联系.
研究的目的:
- 审查支持神经发育调解/调节社会环境对青少年精神疾病影响理论的证据.
- 确定当前研究中一致的发现和局限性.
- 提出一个综合模型和未来的研究方向.
主要方法:
- 关于社会环境,神经发育和精神疾病的人类和动物研究的文献综述.
- 分析支持理论模型的现有证据.
- 综合发现,提出一个新的综合模型.
主要成果:
- 在积极的情感处理过程中增加的条形状反应性与脆弱性有关.
- 较大的海马体积与对社会环境对内化症状影响的敏感性有关.
- 关于神经发育机制的纵向数据有限.
结论:
- 神经发育的变化对社会环境如何影响年轻人的心理健康起着至关重要的作用.
- 一个集成的调解调节模型可以促进理解.
- 需要进一步的纵向研究来阐明这些复杂的关系.
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