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Updated: Jun 20, 2025

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
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Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study

Published on: January 31, 2014

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TopoDoE:一种实验策略的设计,用于在可执行基因调节网络的集合中进行选择和改进

Matteo Bouvier1,2,3, Souad Zreika4, Elodie Vallin4

  • 1Laboratoire de Biologie Moléculaire de la Cellule, Lyon, France. matteo.bouvier@ens-lyon.fr.

BMC bioinformatics
|July 19, 2024
PubMed
概括

这项研究引入了一种新的实验设计策略,以改进基因调节网络 (GRN) 推断. 该方法有效地减少了候选网络,并通过用实验数据验证in silico预测来提高准确性.

关键词:
实验的设计实验的设计可执行的GRN可以执行.GRN 合奏 GRN 合奏 是一个 GRN 合奏.在GRN模拟中使用GRN模拟.基因调节网络推断推断的基因调节网络推断干扰的实验 干扰实验

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Combinatorial Gene Control02:33

Combinatorial Gene Control

Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
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