像病理学家一样思考:通过ChatGPT对肝胆瘤的形态方法
Thiyaphat Laohawetwanit1,2, Sompon Apornvirat1,2, Chutimon Namboonlue3
1Division of Pathology, Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Thailand.
American journal of clinical pathology
|July 20, 2024
概括
将病理学家的形态方法纳入人工智能 (AI) 显著提高了ChatGPT在诊断肝胆瘤的精度. 这种人工智能模型对医学诊断非常有前途.
科学领域:
- 数字病理学数字病理学
- 医学中的人工智能.
- 肝胆病理学 肝胆病理学
背景情况:
- 肝胆瘤的准确诊断对于患者的管理至关重要.
- 组织病理图像分析是肝脏瘤诊断的基石.
- 人工智能 (AI) 具有增强诊断能力的潜力.
研究的目的:
- 为了评估ChatGPT (GPT-4) 在识别肝胆瘤的诊断性能,使用组织病理图像.
- 为了比较不同输入提示的有效性,用于人工智能驱动的基因病理学诊断.
主要方法:
- 这项研究利用了120张肝胆瘤和非瘤性肝脏组织的组织病理学图像.
- 用GPT-4模型测试了两个输入提示:一个模仿病理学家的形态分析,另一个没有.
- 诊断的准确性和一致性被统计分析.
主要成果:
- 使用形态学方法的人工智能模型在诊断各种肝胆瘤和非瘤组织方面明显优于没有这种方法的模型.
- 肝细胞癌,胆道腺瘤和胆管癌的具体改善得到了观察.
- 诊断一致性在形态学方法 (κ=0.46对0.27) 中显著更高.
结论:
- 将类似病理学家的诊断策略集成到AI中,提高了对病理学解释的准确性和一致性.
- 人工智能,特别是在专家诊断过程中接受培训时,在医学诊断中表现出显著的潜力.
- 这项研究强调了人类-人工智能在病理学方面的合作的价值.
相关概念视频
Gross Anatomy of the Liver
2.7K
The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
2.7K
Liver Histology
10.7K
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatocytes perform a variety of essential functions. They secrete...
10.7K
Cirrhosis II: Pathophysiology
42
Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to...
42


