儿童瘤学中的睡眠干预:对证据的系统审查
Lauren C Daniel1, Corinne Catarozoli2, Valerie McLaughlin Crabtree3
1Rutgers University Camden, Camden, New Jersey, USA.
Pediatric blood & cancer
|July 20, 2024
概括
儿童癌症患者在治疗期间和治疗后经常会出现睡眠问题. 这次审查发现了16项关于干预的研究,但大多数都有方法上的局限性,这表明需要更严格的研究.
科学领域:
- 儿科瘤学 儿科瘤学
- 睡眠医学 睡眠医学
- 基于证据的实践.
背景情况:
- 在接受癌症治疗的儿童中,睡眠障碍很普遍.
- 这些睡眠问题可能会持续到生存阶段,影响生活质量.
- 需要确定有效的干预措施来管理这一群体的睡眠问题.
研究的目的:
- 系统地审查针对儿童癌症患者睡眠结果的干预研究.
- 评估治疗期间和治疗后长达五年的干预措施的证据质量.
- 识别差距,指导未来的研究和临床实践.
主要方法:
- 对儿童癌症睡眠的干预研究进行系统的文献搜索.
- 包括睡眠作为主要或次要结果的研究.
- 使用推评估,开发和评价 (GRADE) 系统进行质量评估.
- 包括16项研究,涉及943名参与者.
主要成果:
- 测试了各种干预措施,包括心理教育,压力管理,药物和体育活动.
- 大多数研究的样本规模较小,并且在至少两个领域存在偏差的高风险.
- 没有任何研究被评为在所有领域都有低偏差风险的研究.
结论:
- 确定了几项可行的试点研究,表明了未来研究的潜力.
- 需要进一步进行高质量的研究,以确定儿童癌症相关睡眠问题的干预措施的有效性.
- 调查结果强调,需要改善儿童瘤生存中睡眠障碍的临床管理策略.
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