治疗酒精使用障碍的药物和因酒精戒断住院后的随访:一项多中心研究
Nazima Allaudeen1,2, Joyce Akwe3,4, Cherinne Arundel5,6
1Medical Service, VA Palo Alto Healthcare System, Palo Alto, California, USA.
Journal of hospital medicine
|July 20, 2024
概括
退院治疗显著减少了30天的再入院,并改善了酒精使用障碍 (AUD) 患者的6个月禁欲. 对AUD和标准门诊随访的药物没有显示这些益处.
科学领域:
- 成 药物 药物 药物 药物
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 戒酒是常见的住院原因之一.
- 治疗酒精使用障碍 (AUD) 的药物和门诊随访是标准建议.
- 有限的证据证实了它们在出院后对再接收和禁欲的影响.
研究的目的:
- 评估AUD药物的有效性和对患者再入院和戒断的后续预约.
- 为了确定释放干预措施,以改善AUD的个人释放后的结果.
主要方法:
- 对594名退伍军人进行了回顾性队列研究,他们因酒精戒断而入院.
- 从19家退伍军人卫生管理局医院收集的数据 (2018年10月至2019年9月).
- 后勤回归分析了与30天再入院和6个月禁欲相关的因素.
主要成果:
- 50.7%接受了AUD药物,78.5%进行了后续预约.
- 25.5%的人经历了30天的再入院;17.8%的人实现了6个月的戒断.
- 出院接受住院治疗与更低的再入院率 (AOR 0.39) 和更高的戒断率 (AOR 2.50) 有关.
结论:
- 在酒精戒断住院后,再入院和复发很常见.
- 服用AUD药物和标准的门诊随访并没有改善结果.
- 住院治疗释放是唯一与更好的再录取和戒断率相关的干预措施.
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