在儿科结节性气管支气管支气管炎中的暴露和并存条件
Lauren M C Grant1, Emily Collins2, Karen B Zur3,4
1Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Pediatric pulmonology
|July 20, 2024
概括
儿童的结节性气管支气管炎往往与诸如GERD和消化不良等疾病共存. 在诊断这种气道疾病时,建议对这些因素进行进一步评估.
科学领域:
- 儿科肺病学 儿科肺病学
- 儿科胃肠病学 儿科胃肠病学
背景情况:
- 结节性气管支气管炎是一种影响儿童呼吸道的疾病.
- 了解共存条件对于有效管理至关重要.
研究的目的:
- 调查诊断为结节性气管支气管炎的儿童同时存在的疾病和暴露的患病率.
- 识别疾病病理生理学的潜在促成因素.
主要方法:
- 通过灵活支气管镜检查诊断出结节性气管支气管炎的100名儿童的回顾性审查 (2012-2023年).
- 对同时存在的诊断,支气管支气管洗 (BAL) 结果和胃肠道评估 (EGD,VFSS,阻抗/pH测试) 的分析.
主要成果:
- 胃食道逆流性疾病 (50%) 的高患病率,消化不良/吸收 (40%) 的高患病率,喘 (30%) 的高患病率和埃索诺菲尔性食道炎 (12%).
- BAL显示了与阳性细菌培养 (52%) 和病毒PCR (57%) 相关的中性恋炎症 (63%).
- 胃肠道评估显示了异常吞研究 (60%) 和显著的反流指数.
结论:
- 细菌/病毒感染,GERD,消化不良/吸血和EOE是导致结节性气管支气管炎的潜在因素.
- 在诊断结节性气管支气管炎时,建议对这些情况进行进一步的调查.
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